Tuesday, October 13, 2009

The causes and the specific mechanism that causes Male Pattern Baldness

Research indicates that the amount of androgen in the body has a lot to do with male pattern baldness. Androgen directly affects the lower levels of fertility and hair loss among men.
Men who display male pattern baldness typically have lower levels testosterone, but a proportionately higher level of DHT in their body.
Hormones are not only the main cause of male pattern baldness. There are certain other conditions also like metabolic syndrome, obesity, diabetes, high blood pressure, prostate cancer, and heart diseases.
Male pattern baldness is believed to be genetic in nature. If both sides of the family have histories of male pattern baldness, there is a greater chance for male members to have the condition.
Age is also a contributing factor to hair loss and male pattern baldness. As testosterone levels decrease with age, baldness continually progresses as more and more follicles become sensitized to the hormones.
In women whose ovaries are removed during surgery or destroyed by disease, thinning of scalp hair and increased growth of body hair are not uncommon.

The Specific Mechanism:-

The specific mechanism that causes male pattern baldness is initiated by an androgen called testosterone. Testosterone itself does not cause baldness, when it is acted upon by an enzyme called 5-alpha reductase, a new related hormone is formed called dihydroxytestosterone, or DHT. This causes the follicles of the hair to become sensitized and to turn off their typical renewal cycle.
When the metabolism in the hair follicles slows, the blood supply to the bald area decreases causing the epidermis of the scalp to become more and thinner. This is a result of baldness, not a cause.

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